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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRN3
All Species:
22.12
Human Site:
S635
Identified Species:
40.56
UniProt:
Q9NYV6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYV6
NP_060897.3
651
74107
S635
D
T
H
F
R
S
P
S
S
S
V
G
S
P
P
Chimpanzee
Pan troglodytes
XP_001143837
595
67943
S579
D
T
H
F
R
S
P
S
S
S
V
G
S
P
P
Rhesus Macaque
Macaca mulatta
XP_001108222
651
74080
S635
D
A
H
F
R
S
P
S
S
S
V
G
S
P
P
Dog
Lupus familis
XP_536965
651
74211
A628
D
T
H
F
R
S
P
A
S
S
V
G
S
P
P
Cat
Felis silvestris
Mouse
Mus musculus
B2RS91
656
74499
S633
D
T
H
F
Q
S
P
S
S
S
V
G
S
P
P
Rat
Rattus norvegicus
NP_001129318
661
75125
S638
D
T
H
F
R
S
P
S
S
S
V
G
S
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518561
660
75690
S644
D
A
N
F
R
S
P
S
S
S
V
G
S
P
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001107876
612
69642
G588
G
S
V
E
M
T
P
G
S
F
D
S
H
L
R
Zebra Danio
Brachydanio rerio
XP_706962
612
68744
P597
Y
E
S
H
L
Q
S
P
R
S
V
G
S
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788084
611
70731
K591
L
I
V
D
K
R
P
K
N
F
D
L
S
K
S
Honey Bee
Apis mellifera
XP_001122533
483
56793
I468
I
P
I
L
R
D
N
I
N
N
S
E
H
R
T
Nematode Worm
Caenorhab. elegans
P48322
654
75091
Q637
E
R
T
F
S
C
G
Q
S
S
L
I
N
Y
S
Sea Urchin
Strong. purpuratus
XP_784172
374
42533
A359
L
G
L
T
P
T
S
A
A
C
I
S
P
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
97.6
90.6
N.A.
86.8
85.4
N.A.
76
N.A.
66.8
59.9
N.A.
29.7
27.7
24.4
28.5
Protein Similarity:
100
89
99
94.7
N.A.
92.9
91.8
N.A.
86
N.A.
79.8
76
N.A.
48.8
46.3
42.8
40.7
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
100
N.A.
86.6
N.A.
13.3
40
N.A.
13.3
6.6
20
0
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
93.3
N.A.
26.6
40
N.A.
26.6
20
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
0
16
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% C
% Asp:
54
0
0
8
0
8
0
0
0
0
16
0
0
0
0
% D
% Glu:
8
8
0
8
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
62
0
0
0
0
0
16
0
0
0
0
8
% F
% Gly:
8
8
0
0
0
0
8
8
0
0
0
62
0
8
0
% G
% His:
0
0
47
8
0
0
0
0
0
0
0
0
16
0
0
% H
% Ile:
8
8
8
0
0
0
0
8
0
0
8
8
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% K
% Leu:
16
0
8
8
8
0
0
0
0
0
8
8
0
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
16
8
0
0
8
0
0
% N
% Pro:
0
8
0
0
8
0
70
8
0
0
0
0
8
62
62
% P
% Gln:
0
0
0
0
8
8
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
54
8
0
0
8
0
0
0
0
8
8
% R
% Ser:
0
8
8
0
8
54
16
47
70
70
8
16
70
0
16
% S
% Thr:
0
39
8
8
0
16
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
16
0
0
0
0
0
0
0
62
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _